For Induction of Estrous Cycles in Anestrous Lactating Dairy Cows:

Anestrous dairy cows can be identified using any of the following methods:
- Cows not observed in estrus since calving.
- Cows diagnosed twice without a corpus luteum on either ovary via ultrasonography at a 7 to 14 day interval, such as on Day 35 and Day 42 post calving.
- Cows with low concentration of progesterone in two blood or milk samples collected at a 7 to 14 day interval, such as samples collected on Day 35 and 42 post calving.
Administer one Eazi-Breed CIDR per anestrous cow and remove 7 days later (for example if administered on a Monday remove the following Monday).
If insemination is intended, observe cows on Days 2 to 5 after removal of the Eazi-Breed CIDR Cattle Insert and inseminate animals found in estrus following typical herd practices.

For Synchronization of Estrus in Lactating Dairy Cows:

Administer one Eazi-Breed CIDR per animal and remove 7 days later (for example if administered on a Monday remove the following Monday).
Administer 5 mL LUTALYSE at the time of removal of the EAZI-BREED CIDR Cattle Insert.
Observe animals for signs of estrus on Days 2 to 5 after removal of the Eazi-Breed CIDR and inseminate animals found in estrus following typical herd practices.

For Synchronization of the Return to Estrus in Lactating Dairy Cows Inseminated at the Immediately Preceding Estrus:

Administer one Eazi-Breed CIDR per animal 14±1 days after insemination. Remove Eazi-Breed CIDR Cattle Insert 7 days later (for example, if administered on a Monday remove on the following Monday).
Observe animals for signs of estrus on Days 1 to 3 after removal of the Eazi-Breed CIDR and inseminate animals about 12 hours after onset of estrus.
Note: Do not administer LUTALYSE to cows for synchronization of the return to estrus, as this will interrupt pregnancy that may have occurred at the immediately previous insemination.

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